Heart & Vascular Center

Heart & Vascular Center

Phone Numbers

Lexington Medical Heart and Vascular Center

Cardiology
(803) 744-4900
Cardiothoracic Surgery
(803) 936-3275
Vascular Surgery
(803) 936-7095

Cardiac Rehabilitation

Main Campus
(803) 791-2621
LMC Lexington
(803) 358-6180
LMC Irmo
(803) 732-5388

Research Trials

Ongoing Clinical Trials

  • Access to new treatments before they become available to everyone
  • Driving innovation in research

"These were the best professionals I’ve ever seen. They were amazing."

— Lewis, Heart & Vascular Center Patient

Research Trials

We offer qualifying patients access to the latest clinical trials.

CADFEM

Description
Phase Signal Acquisition (PSAQ) System: Building a Repository of Cardiac Phase Signals for Algorithm Development Recruiting Mostly Female Subjects

Open to enrollment 

Posted By: Dr. Michael Roberts

Posted Date: 4/22/2021

Location: Lexington Heart and Vascular

PHDEV

Description
Repository of Phase Signals for Pulmonary Hypertension Algorithm Development (PHDEV)

Open to enrollment 

Posted By: Dr. Michael Roberts

Posted Date: 7/8/2020

Location: Lexington Heart and Vascular

ILUMIEN IV: OPTIMAL PCI

Description
Randomized trial comparing Optical Coherence Tomography (OCT)-guided stent implantation strategy as compared to an angiography-guided stent implantation strategy in improving clinical cardiovascular outcomes in patients with high-risk clinical characteristics and/or with high-risk angiographic lesions.

Closed to enrollment 

Trial in follow-up

Posted By: Dr. Leonardi

Posted Date: 4/25/2018

Location: Lexington Heart and Vascular

Knocout PE

Description
Observational study designed to understand acoustic pulse thrombolysis (APT) treatment regimens used as standard of care globally for pulmonary embolism.

Closed to enrollment 

Trial in follow-up

Posted By: Dr. Drafts

Posted Date: 2/8/2018

Location: Lexington Heart and Vascular

PFO-PAS

Description
Single arm, multi-center study to confirm the safety and effectiveness of the AMPLATZER™ PFO Occluder in the Post-Approval Setting.

Open to enrollment 

Posted By: Dr. Leonardi

Posted Date: 10/13/2017

Location: Lexington Heart and Vascular

WATCH-TAVR

Description
LMC was one of 20 sites nationally chosen by the Cleveland Clinic. This is a randomized trial evaluating the safety and effectiveness of left atrial appendage occlusion with WATCHMAN™ Device in prevention of stroke and bleeding in patients with atrial fibrillation (AF) undergoing transcatheter aortic valve replacement (TAVR).

Closed to enrollment 

Trial in follow-up

Posted By: Dr. Leonardi

Posted Date: 6/2/2017

Location: Lexington Heart and Vascular

Appraise-ATP

Description
Randomized trial assessing the role of antiachycardia pacing (ATP) in primary prevention patients using ICD therapy.

Closed to enrollment

Trial in follow-up

Posted By: Dr. Malanuk

Posted Date: 10/5/2015

Location: Lexington Heart and Vascular